Lu Guangxiu

Professor, chief physician, distinguished physician of Xiangya, doctoral supervisor, reproductive medicine and medical geneticist, one of the founders of human reproductive engineering in China, director of the National Engineering Research Center for Human Stem Cells, lifetime honorary president and chief scientist of reproductive&genetic hospital of CITIC-Xiangya, director of the National Reference Center for Application of Genetic Testing Technology - Prepregnancy Diagnosis Center. She was a member of the Standing Committee of the CPPCC National Committee, chairman of the Jiusan Society of Hunan Province, vice chairman of the CPPCC Hunan Province, and director of the Institute of Reproductive and Stem Cell Engineering of Central South University.
In the 1980s, Lu Guangxiu established a relatively comprehensive human assisted reproductive technology system in China, initiated infertility and genetic counseling clinics, and achieved significant accomplishments:
With her and her team’s effort,
 In 1981, a human sperm bank was established.
 In 1983, a baby was conceived through artificial insemination with frozen semen.
 In 1988,two IVF babies were born.
In 1990, the mouse embryo genetic diagnosis model of preimplantation embryo was established and successfully applied in human.
In 1991, a healthy baby was conceived after the treatment of malformed sperm separation.
In 1993,the sperm microinsemination model was established.
In 2000, a "test tube baby" using ultra-rapid frozen embryo transfer was conceived.
In 2005, a healthy baby free of Duchenne muscular dystrophy (DMD) was successfully delivered following preimplantation genetic diagnosis (PGD) to exclude the genetic disorder.
In 2012, PGD/PGS test-tube babies utilizing whole-genome sequencing (WGS) technology were born.
In 2015, "cancer-free baby" was born;
In 2016, a healthy baby excluded chromosome balance translocation  utilizing MicroSeq was born.
Up to now, there are a total of more than 220,000 healthy babies born with artificial assisted pregnancy. According to Nature in 2017, the amount of assisted reproductive treatment in a year is equivalent to about 1/4 of the United States, which has won the trust and praise from patients. Under her leadership, the research team has established clinical protocols enabling reproductive intervention for 1,064+ monogenic diseases,achieving primary implementation of positive eugenics.
In the field of human embryonic stem cell research and application, led by Professor Lu Guangxiu, the research team was granted approval by the National Development and Reform Commission to establish National Engineering Research Center for Human Stem Cells,and was designated as a Key Laboratory of Human Stem Cells and Reproductive Engineering under the Ministry of Health in 2005. The center generated human somatic cell-cloned blastocysts,which has attracted widespread attention from international peers.This research has been reported by the Wall Street newspaper and the British Times column,and she had been featured in Nature and other international renowned academic journals. In addition, the center has established a human embryonic stem cell line and now owns an embryonic stem cell bank with independent intellectual property rights, with a stock of more than 500 human embryonic stem cell lines, providing sufficient seed sources for regenerative medicine.
Due to her outstanding contributions in reproductive medicine and stem cell research, she has won the second prize of National Science and Technology Progress twice. Her distinguished achievement also earned her numerous accolades such as "National Outstanding Contribution of Science and technology experts", "National March 8th Red-Banner Pacesetter", “China’s Top Ten Outstanding Women", "National Advanced Workers", "National May 1st Labor Medal", "National Excellent Teacher", "Chinese Population Award", "National Jiusan Model", "National Renowned Physician", “ China’s Good Samaritans in Dedication and Professionalism ", "Hunan Provincial Science and Technology Outstanding Contribution Award", "Hunan Province Moral Model" .
She has undertaken a number of national research projects including key projects of the National Natural Science Foundation, 863 and 973 projects. She published six monographs, among which "Human Reproduction and Reproductive Engineering" is the earliest monograph on human assisted reproductive technology in China. As of June 2017, she has published 572 papers , including 80 papers in SCI-indexed journals, and obtained 24 international and domestic patents.As a doctoral supervisor in developmental biology, genetics, reproductive medicine, stem cell and regenerative medicine, and bioethics, she has trained a large number of professionals in human assisted reproduction and stem cell research for our country.